Levonorgestrel IMpurity R

Name	13-beta-ethyl-3-methoxygona-2,5(10)-dien-17-one
Synonyms	Methoxydienone na-2,5(10)-dien-17-one 13-beta-Ethyl-3-methoxy- Levonorgestrel IMpurity R Methoxydienone Max LMG 3-Mehoxy-18-Methyestra-2,5(10)-dien-17-one Gona-2,5(10)-dien-17-one,13-ethyl-3-Methoxy- 13-beta-ethyl-3-methoxygona-2,5(10)-dien-17-one (13S)-13β-Ethyl-3-methoxygona-2,5(10)-dien-17-one (8R,9S,13S,14S)-13-ethyl-3-methoxy-1,4,6,7,8,9,11,12,13,14,15,16-dodecahydro-17H-cyclopenta[a]phenanthren-17-one (non-preferred name)
CAS	2322-77-2
EINECS	219-034-4
InChI	InChI=1/C20H28O2/c1-3-20-11-10-16-15-7-5-14(22-2)12-13(15)4-6-17(16)18(20)8-9-19(20)21/h5,16-18H,3-4,6-12H2,1-2H3/t16-,17-,18+,20+/m1/s1

Molecular Formula	C20H28O2
Molar Mass	300.44
Density	1.09±0.1 g/cm3(Predicted)
Melting Point	122-124 °C
Boling Point	448.0±45.0 °C(Predicted)
Flash Point	188.8°C
Water Solubility	270μg/L at 20℃
Vapor Presure	0Pa at 25℃
Appearance	White or off-white crystalline powder
Storage Condition	Room Temprature
Refractive Index	1.551
Physical and Chemical Properties	Crystalline compound. Melting point 150-160 °c.

LogP	5.86 at 25℃
Use	18-Methyl norethindrone, trienoxone intermediate. Protein anabolic hormone is an anabolic drug, which has the characteristics of promoting protein synthesis and reducing amino acid decomposition. It can promote muscle proliferation, improve movement strength and enhance male sexual characteristics. These drugs are often used in medical practice for chronic consumptive diseases
Production method	Use 3-methoxy -18-methyl -1,3,5(10),8-estradiene -17-One is successively reduced with potassium borohydride and lithium-ammonia to generate 3-methoxy -18-methyl 2,5(10) estradiene -17-alcohol, the product is then prepared by cyclohexanone-isopropanol aluminum oxidation (Wareth oxidation).

Last Update：2024-04-10 22:29:15

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